New remedy for Lupus

Systemic lupus erythematosus (SLE) is a persistent autoimmune disease characterized by the body's immune system

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A person with SLE may experience a wide range of signs and symptoms, including joint and muscle pain, irritation, and fever.

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Diagnosis of the disorder can often take time, and treatment options are limited.

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Health care providers commonly prescribe medications such as hydroxychloroquine

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The team evaluated genes that manage iron in T cells and discovered a transferrin receptor (CD71) that takes up iron in cells

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In addition, they found that this receptor was more specifically expressed in T cells from humans

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This elevated expression caused the T cells to take up too much iron.

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While the scientists blocked CD71 with an antibody, T cell iron levels decreased, decreasing T cell inflammatory

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