Mire suggests how most liver cancers hijack the
internal cells of the circadian clock mechanism
The most common form of liver cancer, hepatocellular carcinoma (HCC), is already the
third leading reason for most cancer-related deaths worldwide
and cases are increasing, both in the US and in the United States.
like in the United States. like in the world.
While chemotherapy, surgery, and liver transplants
may help some patients
HCC-specific remedies may save hundreds of thousands
Current research has provided clues to
a potential target: circadian clock proteins inside cells
for example, the observation that accumulated cells from liver
cancer patients have disrupted circadian rhythms.
Now, a study led by researchers at the USC Keck School of Medicine not only links circadian
clock proteins to most liver cancers
but also suggests exactly how cancer cells hijack the circadian
clock machinery to divide.
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